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CD83分子(CD83)重組蛋白

編號(hào)RPB845Ra02
物種Rattus norvegicus (Rat，大鼠)相同的名稱，不同的物種。
來源原核表達(dá)
宿主E.coli
內(nèi)毒素水平<1.0EU/µg(LAL法測定)
亞細(xì)胞定位細(xì)胞膜
預(yù)測分子量42.6kDa
實(shí)際分子量46kDa(差異分析請(qǐng)參閱說明書)
片段與標(biāo)簽Met22~Glu135 with N-terminal His and GST Tag
緩沖液成份PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
性狀凍干粉
純度> 95%
等電點(diǎn)7.6
應(yīng)用Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請(qǐng)參見活性蛋白。
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規(guī)格10μg50μg200μg1mg5mg
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Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

避免反復(fù)凍融。2-8°C不超過一個(gè)月，-80°C不超過12個(gè)月。

熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲(chǔ)，損失率低于5%。

雜志	參考文獻(xiàn)
Immunobiology.	Murine CD83-positive T cells mediate suppressor functions in vitro and in vivo[Pubmed:25151500]
PLoS One	The Polyunsaturated Fatty Acids Arachidonic Acid and Docosahexaenoic Acid Induce Mouse Dendritic Cells Maturation but Reduce T-Cell Responses In Vitro[PubMed: 26619195]
Scientific Reports COMMUNICATIONS	NK cells are negatively regulated by sCD83 in experimental autoimmune uveitis[pubmed:29038541]
Frontiers in Immunology	A Kinetic Study of CD83 Reveals an Upregulation and Higher Production of sCD83 in Lymphocytes from Pregnant Mice.[pubmed:28491062]
Frontiers in Immunology	Soluble CD83 Alleviates Experimental Autoimmune Uveitis by Inhibiting Filamentous Actin-Dependent Calcium Release in Dendritic Cells[Pubmed:30050530]
THERIOGENOLOGY	Porcine soluble CD83 alleviates LPS-induced abortion in mice by promoting Th2 cytokine production, Treg cell generation and trophoblast invasion[Pubmed: 32810792]

編號(hào)	適用物種：Rattus norvegicus (Rat，大鼠)	應(yīng)用(僅供研究使用，不用于臨床診斷！)
RPB845Ra01	CD83分子(CD83)重組蛋白	Positive Control; Immunogen; SDS-PAGE; WB.
RPB845Ra02	CD83分子(CD83)重組蛋白	Positive Control; Immunogen; SDS-PAGE; WB.